Methylamine → HCID 13136976, compound

HRID 851219Notes

Reaction equation

HRID 851219 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]2[C:9]3[CH2:14][CH2:13][N:12]([CH2:15][C:16](=O)[CH3:17])[CH2:11][C:10]=3[C:19](=[O:21])[O:20][C:5]=2[CH:4]=1.[CH3:22][NH2:23]>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]2[C:9]3[CH2:14][CH2:13][N:12]([CH2:15][CH:16]([NH:23][CH3:22])[CH3:17])[CH2:11][C:10]=3[C:19](=[O:21])[O:20][C:5]=2[CH:4]=1

Participants

3

Reactant 2

HCID 6329MethylamineHCID 13136938HCID 13136938, compound

Product 1

HCID 13136976HCID 13136976, compoundYield 69.6%

Procedure

Prepared by the method described for Example 51 from 1,2,3,4-tetrahydro-8-methoxy-3-(2-oxopropyl)-5H-[1]benzopyrano[3,4-c]pyridin-5-one (16.5 g, 0.057 moles) and methylamine (8 ml, 0.18 moles). Recrystallization from ethyl acetate gave the product (12.0 g), mp 109°-111° C.

Workup

  1. customPrepared by the method
  2. customRecrystallization from ethyl acetate

Sources & evidence

ORD record
ord-4e35a1afc79e43138a241a9942e784c4
Source dataset
uspto-grants-1983_05
Patent number
US04382939

Reaction notes

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