Trimethyl phosphite → Phosphinecarboxylic acid, dimethoxy-, butyl ester, oxide

HRID 851705Notes

Reaction equation

HRID 851705 reaction equation
C[O:2][P:3]([O:6][CH3:7])[O:4][CH3:5].Cl[C:9]([O:11][CH2:12][CH2:13][CH2:14][CH3:15])=[O:10]>>[CH2:12]([O:11][C:9]([P:3](=[O:2])([O:6][CH3:7])[O:4][CH3:5])=[O:10])[CH2:13][CH2:14][CH3:15]

Participants

3

Reactant 2

HCID 8472Trimethyl phosphiteHCID 61140Butyl chloroformate

Product 1

HCID 512108Phosphinecarboxylic acid, dimethoxy-, butyl ester, oxide

Procedure

From 10.0 ml (85 mmole) of trimethylphosphite and 8.7 g (64 mmole) of n-butyl chloroformate. (100° C., 1.5 hours). Yield 10.9 g (81%). Bp1.0 97°-100° C. nD25 1,4269.

Workup

  1. custom(100° C., 1.5 hours)
  2. customBp1.0 97°-100° C.

Sources & evidence

ORD record
ord-ba4cc6d1032a4712a11df0aa739d8dbf
Source dataset
uspto-grants-1983_05
Patent number
US04386081

Reaction notes

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