Isopropyl chloroformate → Phosphinecarboxylic acid, dimethoxy-, 1-methylethyl ester, oxide

HRID 851706Notes

Reaction equation

C[O:2][P:3]([O:6][CH3:7])[O:4][CH3:5].Cl[C:9]([O:11][CH:12]([CH3:14])[CH3:13])=[O:10]>>[CH:12]([O:11][C:9]([P:3](=[O:2])([O:6][CH3:7])[O:4][CH3:5])=[O:10])([CH3:14])[CH3:13]

Participants

Reactant 2

HCID 7917Isopropyl chloroformate

HCID 8472Trimethyl phosphite

Product 1

HCID 512107Phosphinecarboxylic acid, dimethoxy-, 1-methylethyl ester, oxide

Procedure

From 10.0 ml (85 mmole) of trimethylphosphite and 7.8 g (64 mmole) of i-propyl chloroformate. (100° C., 2 hours). Yield 8.0 g (64%). Bp2 90°-2° C. nD25 1,4202.

Workup

custom(100° C., 2 hours)
customBp2 90°-2° C.

Sources & evidence

ORD record: ord-9f7924b51e93442ebea3ff9b2f82267e
Source dataset: uspto-grants-1983_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04386081

Reaction notes

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