反应详情

A suspension of 500 mg (1.34 mmol) of the product obtained in Step A and 978 μl (20.13 mmol) of hydrazine monohydrate in a mixture of MeOH (30 ml) and DMF (6 ml) is refluxed for 24 hours. The MeOH is evaporated off, water is added to the reaction mixture and the precipitate, which corresponds to the title product, is filtered off.

1. temperatureis refluxed for 24 hours
2. customThe MeOH is evaporated off
3. additionwater is added to the reaction mixture
4. filtrationis filtered off