3,5-Dichloroaniline → 2-[2-(3,5-dichlorophenyl)-2H-tetrazol-5-yl]pyridine

HRID 852333Notes

Reaction equation

HRID 852333 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[N:12]=[N:11][C:10]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=3)=[N:9]2)[CH:5]=[CH:6][CH:7]=1.[Cl:19]C1C=C(C=C(Cl)C=1)N.N1C=CC=CC=1C=O>>[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[N:12]=[N:11][C:10]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=3)=[N:9]2)[CH:5]=[C:6]([Cl:19])[CH:7]=1

Participants

4

Reactant 3

HCID 122813,5-DichloroanilineHCID 142732-PyridinecarboxaldehydeHCID 99213692-[2-(3-chlorophenyl)-2H-tetrazol-5-yl]pyridine

Product 1

HCID 691520682-[2-(3,5-dichlorophenyl)-2H-tetrazol-5-yl]pyridine

Procedure

Following the procedure described in EXAMPLE 1 for the synthesis of 2-[2-(3-chlorophenyl)-2H-tetrazol-5-yl]pyridine, 3,5-dichloroaniline (48.6 mg, 0.3 mmol) and 2-pyridinecarboxaldehyde (32.1 mg, 0.3 mmol) were employed to obtain 2-[2-(3,5-dichlorophenyl)-2H-tetrazol-5-yl]pyridine as an orange solid.

Sources & evidence

ORD record
ord-047c781330624742be457d800bbf1366
Source dataset
uspto-grants-2007_08
Patent number
US07253190B2

Reaction notes

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