Dimethylformamide dimethyl acetal → HCID 72466434, compound

HRID 852439Notes

Reaction equation

HRID 852439 reaction equation
[NH:1]([C:5]1[CH:6]=[C:7]([S:11]([NH2:14])(=[O:13])=[O:12])[CH:8]=[CH:9][CH:10]=1)[C:2]([NH2:4])=[S:3].CO[CH:17](OC)[N:18]([CH3:20])[CH3:19]>>[CH3:17][N:18]([CH:20]=[N:14][S:11]([C:7]1[CH:8]=[CH:9][CH:10]=[C:5]([NH:1][C:2]([N:4]=[CH:17][N:18]([CH3:20])[CH3:19])=[S:3])[CH:6]=1)(=[O:12])=[O:13])[CH3:19]

Participants

3

Reactant 2

HCID 78373Dimethylformamide dimethyl acetalHCID 431489173-[(Aminothioxomethyl)amino]benzenesulfonamide

Product 1

HCID 72466434HCID 72466434, compoundYield 82%

Procedure

A mixture of 2.3 g (9.9 mmol) 3-Thioureido-benzenesulfonamide and 17 ml N,N-Dimethylformamide dimethyl acetal was heated for 2 h to 90° C. The precipitate was filtered of washed with DCM/diethyl ether 1:3 and dried to yield 2.8 g (82%) of the title compound.

Workup

  1. temperaturewas heated for 2 h to 90° C
  2. filtrationThe precipitate was filtered
  3. washof washed with DCM/diethyl ether 1:3
  4. customdried

Sources & evidence

ORD record
ord-4452ed59d260418a942b5ff2ee2dd0e4
Source dataset
uspto-grants-2007_08
Patent number
US07253197B2

Reaction notes

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