反应详情

A solution of 21 (6.7 mg, 0.019 mmol) in a 1:1 solution of CH2Cl2:MeOH was stirred with TFA (3 μL, 0.038 mmol) at room temperature for 2 hours when complete conversion was observed by LCMS. The solution was dried in vacuo and the residue was washed with hexanes to yield 7 mg of the product 22. EI MS (m/z) 355.4 [MH+].

1. customThe solution was dried in vacuo
2. washthe residue was washed with hexanes