4-Methoxyphenol → HCID 23516352, compound

HRID 855465Notes

Reaction equation

HRID 855465 reaction equation
[C:1]([O:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][O:12][C:13]1[CH:34]=[CH:33][C:16]([C:17]([O:19][C:20]2[CH:32]=[CH:31][C:23]([C:24]([O:26]COCC)=[O:25])=[CH:22][CH:21]=2)=[O:18])=[CH:15][CH:14]=1)(=[O:4])[CH:2]=[CH2:3].C1(C)C=CC(S([O-])(=O)=O)=CC=1.[NH+]1C=CC=CC=1.COC1C=CC(O)=CC=1>C(O)C>[C:1]([O:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][O:12][C:13]1[CH:34]=[CH:33][C:16]([C:17]([O:19][C:20]2[CH:32]=[CH:31][C:23]([C:24]([OH:26])=[O:25])=[CH:22][CH:21]=2)=[O:18])=[CH:15][CH:14]=1)(=[O:4])[CH:2]=[CH2:3]

Participants

5

Reactant 3

HCID 90154-MethoxyphenolHCID 466102Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1)HCID 58935103HCID 58935103, compound

Product 1

HCID 23516352HCID 23516352, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
60 °C

Procedure

98.5 g (0.2 mole) of ethoxymethyl 4-(4-(6-acryloyloxyhexyloxy)bezoyloxy)benzoate (16) were dissolved in 400 ml of ethanol and 5 g (0.02 mole) of pyridinium 4-toluensulfonate and 20 mg of 4-methoxyphenol were added. The mixture was heated at 60° C. for 15 h. After cooling down at room temperature the product crystallized. It was collected, washed with 300 ml of ethanol, and dried in a desiccator 55.3 g of a white powder (67%) were obtained.

Workup

  1. temperatureAfter cooling down at room temperature the product
  2. customcrystallized
  3. customIt was collected
  4. washwashed with 300 ml of ethanol
  5. dry with materialdried in a desiccator 55.3 g of a white powder (67%)
  6. customwere obtained

Sources & evidence

ORD record
ord-c7e3d486a2f946e1af110cddf6235b3c
Source dataset
uspto-grants-2007_08
Patent number
US07261836B2

Reaction notes

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