Tetrahydrofuran → [5-(3,5-Bis-trifluoromethyl-benzenesulfonylamino)-3-chloro-2-fluoro-5,6,7,8-tetrahydro-naphthalen-1-yloxy]-acetic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH2:7][O:8][c:9]1[c:10]([F:21])[c:11]([Cl:20])[cH:12][c:13]2[c:18]1[CH2:17][CH2:16][CH2:15][CH:14]2[NH2:19])=[O:22].[CH:41]([N:42]([CH:43]([CH3:44])[CH3:45])[CH2:46][CH3:47])([CH3:48])[CH3:49].[F:23][C:24]([c:25]1[cH:26][c:27]([S:35](=[O:36])(=[O:37])[Cl:38])[cH:28][c:29]([C:31]([F:32])([F:33])[F:34])[cH:30]1)([F:39])[F:40].[O:50]1[CH2:51][CH2:52][CH2:53][CH2:54]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH2:7][O:8][c:9]1[c:10]([F:21])[c:11]([Cl:20])[cH:12][c:13]2[c:18]1[CH2:17][CH2:16][CH2:15][CH:14]2[NH:19][S:35]([c:27]1[cH:26][c:25]([C:24]([F:23])([F:39])[F:40])[cH:30][c:29]([C:31]([F:32])([F:33])[F:34])[cH:28]1)(=[O:36])=[O:37])=[O:22]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-36218a92965f4f1f8099f88ab1aae5f2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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