2,5-Dimethoxyaniline → 2-(3-Chloro-4-hydroxy-phenyl)-benzooxazol-5-ol

HRID 858212Notes

Reaction equation

HRID 858212 reaction equation
[CH3:1][O:2][C:3]1[CH:9]=[CH:8][C:7]([O:10]C)=[CH:6][C:4]=1[NH2:5].[Cl:12][C:13]1[CH:14]=[C:15]([CH:19]=[CH:20][C:21]=1[O:22]C)C(O)=O>>[Cl:12][C:13]1[CH:14]=[C:15]([C:1]2[O:2][C:3]3[CH:9]=[CH:8][C:7]([OH:10])=[CH:6][C:4]=3[N:5]=2)[CH:19]=[CH:20][C:21]=1[OH:22]

Participants

3

Reactant 2

HCID 76132,5-DimethoxyanilineHCID 1699823-Chloro-p-anisic acid

Product 1

HCID 1354432802-(3-Chloro-4-hydroxy-phenyl)-benzooxazol-5-ol

Procedure

The title compound was prepared in substantially the same manner as described in Example 1, from 2,5-dimethoxyaniline, and 3-chloro-4-methoxybenzoic acid and was obtained as a white solid, m.p. 254–256° C.; MS m/e 260 (M−H)+.

Workup

  1. customwas obtained as a white solid, m.p. 254–256° C.

Sources & evidence

ORD record
ord-31a69f4bd9fa4290b39a2478112a5327
Source dataset
uspto-grants-2006_12
Patent number
US07148247B2

Reaction notes

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