1-Chloro-4-iodobenzene → tert-Butyl N-[4-(4-chlorophenyl)-2-nitro-phenyl]carbamate

HRID 859271Notes

Reaction equation

HRID 859271 reaction equation
[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[CH:12][C:11](I)=[CH:10][C:9]=1[N+:15]([O-:17])=[O:16])([CH3:4])([CH3:3])[CH3:2].B1(B2OC(C)(C)C(C)(C)O2)OC(C)(C)C(C)(C)O1.[Cl:37][C:38]1[CH:43]=[CH:42][C:41](I)=[CH:40][CH:39]=1>>[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:41]2[CH:42]=[CH:43][C:38]([Cl:37])=[CH:39][CH:40]=2)=[CH:10][C:9]=1[N+:15]([O-:17])=[O:16])([CH3:4])([CH3:3])[CH3:2]

Participants

4

Reactant 3

HCID 125101-Chloro-4-iodobenzeneHCID 2733548Bis(pinacolato)diboraneHCID 23554339Tert-butyl (4-iodo-2-nitrophenyl)carbamate

Product 1

HCID 69592790tert-Butyl N-[4-(4-chlorophenyl)-2-nitro-phenyl]carbamate

Procedure

Prepared from (4-iodo-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example A1), bis(pinacolato)diboron and 1-chloro-4-iodobenzene according to the general procedure C. Obtained as a yellow solid (779 mg).

Sources & evidence

ORD record
ord-1a18b7bb5121482894e2e47344a6784a
Source dataset
uspto-grants-2006_12
Patent number
US07151098B2

Reaction notes

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