Stannous chloride dihydrate → HCID 69592764, compound

HRID 859300Notes

Reaction equation

HRID 859300 reaction equation
[C:1]([O:5][C:6](=[O:26])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]#[C:15][C:16]2[CH:21]=[CH:20][C:19]([CH3:22])=[CH:18][CH:17]=2)=[CH:10][C:9]=1[N+:23]([O-])=O)([CH3:4])([CH3:3])[CH3:2].O.O.Cl[Sn]Cl>>[C:1]([O:5][C:6](=[O:26])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]#[C:15][C:16]2[CH:21]=[CH:20][C:19]([CH3:22])=[CH:18][CH:17]=2)=[CH:10][C:9]=1[NH2:23])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 61436Stannous chloride dihydrateHCID 69592839HCID 69592839, compound

Product 1

HCID 69592764HCID 69592764, compoundYield 97%

Procedure

Prepared from (2-nitro-4-p-tolylethynyl-phenyl)-carbamic acid tert.-butyl ester (Example F4) (640 mg, 1.82 mmol) by reduction with SnCl2.2H2O (2.0 g, 9.1 mmol) according to the general procedure G (method b). Obtained as a beige solid (569 mg).

Sources & evidence

ORD record
ord-c8f079c8b94d492889e73881ec56748b
Source dataset
uspto-grants-2006_12
Patent number
US07151098B2

Reaction notes

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