Ethyl Acetate → HCID 45087000, compound

HRID 861001Notes

Reaction equation

HRID 861001 reaction equation
[Br:1][C:2]1[CH:3]=[N:4][CH:5]=[C:6]([CH:13]=1)[C:7]([NH:9][CH:10]1[CH2:12][CH2:11]1)=[O:8].CC[O:16]C(C)=O>CO>[CH2:12]1[CH:10]([NH:9][C:7]([C:6]2[CH:5]=[N+:4]([O-:16])[CH:3]=[C:2]([Br:1])[CH:13]=2)=[O:8])[CH2:11]1

Participants

4

Reactant 2

HCID 8857Ethyl AcetateHCID 6042285-Bromo-N-cyclopropylpyridine-3-carboxamide

Product 1

HCID 45087000HCID 45087000, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Prepared according to the procedure described in EXAMPLE 9 (Step 4) but using 5-bromo-N-cyclopropyl-nicotinamide from Step 1 as starting material. Flash chromatography (EtOAc:MeOH; 9:1) afforded the title compound as a white solid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-b996ee0a3c5a46e6a64046a2e9bbd224
Source dataset
uspto-grants-2006_12
Patent number
US07153968B2

Reaction notes

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