2-ethylhexanoic acid tin(II) salt → HCID 131720449, compound

HRID 861179Notes

Reaction equation

HRID 861179 reaction equation
[C:1]1(=[O:8])[O:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:9]1[O:16][C:14](=[O:15])[CH2:13][O:12][C:10]1=[O:11].[O:17]1[CH2:22][CH2:21][O:20][CH2:19][C:18]1=[O:23].CCCCC(C([O-])=O)CC.CCCCC(C([O-])=O)CC.[Sn+2]>C(O)(C(F)(F)F)C(F)(F)F.C(O)COCCO>[C:1]1(=[O:8])[O:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:9]1[O:16][C:14](=[O:15])[CH2:13][O:12][C:10]1=[O:11].[O:17]1[CH2:22][CH2:21][O:20][CH2:19][C:18]1=[O:23]

Participants

7

Reactant 4

HCID 93182-ethylhexanoic acid tin(II) saltHCID 10401epsilon-CAPROLACTONEHCID 18233DioxanoneHCID 65432Glycolide

Product 1

HCID 131720449HCID 131720449, compound

Reagents, catalysts & solvents 2

HCID 8117Diethylene GlycolSolventHCID 135291,1,1,3,3,3-Hexafluoro-2-propanolSolvent

Procedure

The procedure described in Example 2 is substantially reproduced with 45.66 gm (0.40 mole) of ε-caprolactone, 63.84 gm (0.55 mole) of glycolide, 5.10 gm (0.05 mole) of p-dioxanone, 0.114 ml (1.20 mmole/mole of total monomer) of distilled diethylene glycol and 0.0673 ml stannous octoate (0.33 molar solution is toluene). A weight loss of 1.6% is observed when the polymer is devolatilized at 110° C. under high vacuum. The I.V. of the copolymer is 1.51 dl/g in HFIP and the mole ratio of PCL/PGA/PDS is found to be 38.5/56.2/5.4 by NMR. The glass transition temperature (Tg) and the melting point (Tm) of this copolymer are found to be -6° C. and 54° C., respectively, by DSC.

Workup

  1. customis devolatilized at 110° C. under high vacuum
  2. customto be -6° C. and 54° C.

Sources & evidence

ORD record
ord-8f1d92909dec437aa1de88769f191703
Source dataset
uspto-grants-1998_02
Patent number
US05713920

Reaction notes

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