反应详情

The product of Example 2 (24.89 g, 96 mmol) and 10% (v/v) H2SO4 (100 mL) were combined in a 250 mL flask. The reaction was heated to reflux for 8 h and then cooled to room temperature. The reaction was made basic with aq K2CO3 and extracted with EtOAc. The extracts were dried (MgSO4), decolorized with activated charcoal, and filtered. Removal of all solvent in vacuo gave 8.49 g (71%) of the desired product.

1. temperatureThe reaction was heated
2. temperatureto reflux for 8 h
3. extractionextracted with EtOAc
4. dry with materialThe extracts were dried (MgSO4)
5. filtrationfiltered
6. customRemoval of all solvent in vacuo