Triethylamine → N,N,N-Triethyl-2-hydroxyethan-1-aminium bromide

HRID 862138Notes

Reaction equation

HRID 862138 reaction equation
[Br:1][CH:2]([OH:4])[CH3:3].[CH2:5]([N:7]([CH2:10][CH3:11])[CH2:8][CH3:9])[CH3:6]>ClCCl>[Br-:1].[OH:4][CH2:2][CH2:3][N+:7]([CH2:10][CH3:11])([CH2:8][CH3:9])[CH2:5][CH3:6]

Participants

4

Reactant 2

HCID 8471TriethylamineHCID 14202443Ethanol, 1-bromo-

Product 1

HCID 15419000N,N,N-Triethyl-2-hydroxyethan-1-aminium bromideYield 41%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Hydroxyethyltriethylammonium bromide was obtained as follows: ##STR14## Bromoethanol (distilled, 2 g, 16 mmole) and triethylamine (1.62 g, 16 mmole) were heated in dichloromethane (30 ml) at 40° C. for 16 hours. After cooling the precipitate was filtered and dried over phosphorus pentoxide to yield hydroxyethyltriethylammonium bromide as a white powder, 1.47 g, 6.5 mmole, 41% yield.

Workup

  1. temperatureAfter cooling the precipitate
  2. filtrationwas filtered
  3. dry with materialdried over phosphorus pentoxide

Sources & evidence

ORD record
ord-ce3fd3ecd882480d8c88a83381d44cb1
Source dataset
uspto-grants-1998_02
Patent number
US05717047

Reaction notes

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