HCID 54237649, compound → HCID 10316940, compound

HRID 862949Notes

Reaction equation

HRID 862949 reaction equation
[CH2:1]1[O:9][C:8]2[CH:7]=[CH:6][C:5]([CH:10]=[C:11]([C:16](=[O:27])[C:17]3[CH:22]=[CH:21][CH:20]=[C:19]([O:23][CH2:24][CH2:25][CH3:26])[CH:18]=3)[C:12]([O:14][CH3:15])=[O:13])=[CH:4][C:3]=2[O:2]1>FC(F)(F)C(O)=O>[CH3:15][O:14][C:12]([CH:11]1[C:16](=[O:27])[C:17]2[C:22](=[CH:21][CH:20]=[C:19]([O:23][CH2:24][CH2:25][CH3:26])[CH:18]=2)[CH:10]1[C:5]1[CH:6]=[CH:7][C:8]2[O:9][CH2:1][O:2][C:3]=2[CH:4]=1)=[O:13]

Participants

3

Reactant 1

HCID 54237649HCID 54237649, compound

Product 1

HCID 10316940HCID 10316940, compoundYield 868.7%

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

Methyl 3-(3,4-methylenedioxyphenyl)-2-[3-(prop-1-yloxy)benzoyl]propenoate (7.4 g, 2.0 mmol) was dissolved in trifluoroacetic acid (50 mL) at 0° C. and the mixture stirred at room temperature for 20 min.. The trifluoroacetic acid was removed in vacuo to give the title compound (6.4 g, 87 %) as a white solid after trituration with warm isopropanol m.p. 106°-108° C. Anal. Calc. for C21H20O6 : C, 68.47; H, 5.47. Found: C, 68.12; H, 5.41.

Workup

  1. customThe trifluoroacetic acid was removed in vacuo

Sources & evidence

ORD record
ord-9efe1439383c40748cd677345b4ddc05
Source dataset
uspto-grants-1998_02
Patent number
US05719182

Reaction notes

Loading…