Potassium Cation → 4-[4-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)pyrazolo[3,4-d]pyrimidin-1-yl]-piperidine-1-carboxylic acid tert-butyl ester

HRID 86331Notes

Reaction equation

HRID 86331 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([n:14]2[n:15][cH:16][c:17]3[c:18]2[n:19][cH:20][n:21][c:22]3[Cl:23])[CH2:12][CH2:13]1.[C:34](=[O:35])([O-:36])[O-:37].[CH3:40][CH2:41][O:42][C:43](=[O:44])[CH3:45].[CH3:46][N:47]([CH3:48])[CH:49]=[O:50].[K+:38].[K+:39].[OH2:51].[nH:24]1[cH:25][cH:26][c:27]2[c:28]1[n:29][cH:30][c:31]([OH:33])[cH:32]2>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([n:14]2[n:15][cH:16][c:17]3[c:18]2[n:19][cH:20][n:21][c:22]3[O:33][c:31]2[cH:30][n:29][c:28]3[nH:24][cH:25][cH:26][c:27]3[cH:32]2)[CH2:12][CH2:13]1

Participants

8

Reactant 7

HCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 220307221H-Pyrrolo[2,3-b]pyridin-5-olHCID 57964905Tert-butyl 4-(4-chloro-1H-pyrazolo[3,4-D]pyrimidin-1-YL)piperidine-1-carboxylate

Product 1

HCID 579650464-[4-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)pyrazolo[3,4-d]pyrimidin-1-yl]-piperidine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-2a2c3bc7d150479885ff1c1c2ab41831
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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