HCID 19430424, compound → HCID 19430414, compound

HRID 863449Notes

Reaction equation

HRID 863449 reaction equation
[C:1]1([C:7]2[S:11][C:10]3[C:12]([C:16](OC)=[O:17])=[CH:13][CH:14]=[CH:15][C:9]=3[CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[H-].[H-].[H-].[H-].[Li+].[Al+3]>O1CCCC1>[OH:17][CH2:16][C:12]1[C:10]2[S:11][C:7]([C:1]3[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=3)=[CH:8][C:9]=2[CH:15]=[CH:14][CH:13]=1

Participants

4

Reactant 2

HCID 19430424HCID 19430424, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 19430414HCID 19430414, compoundYield 85%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent2×

Procedure

20 g of the compound from Example VI are dissolved in 75 ml of tetrahydrofuran and the solution is added dropwise to 40 mmol of LiAlH4 in 50 ml of tetrahydrofuran. Customary working up gives 85% of the title compound.

Sources & evidence

ORD record
ord-38043b263b3b4259b3fc088f4c730a83
Source dataset
uspto-grants-1998_02
Patent number
US05721248

Reaction notes

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