Acetic Acid → 1-Benzylpiperidin-3-ol

HRID 86374Notes

Reaction equation

HRID 86374 reaction equation
[C:16]([O:17][BH-:18]([O:19][C:20](=[O:21])[CH3:22])[O:23][C:24](=[O:25])[CH3:26])(=[O:27])[CH3:28].[C:30](=[O:31])([OH:32])[O-:33].[CH3:35][c:36]1[cH:37][cH:38][cH:39][cH:40][cH:41]1.[CH3:42][C:43](=[O:44])[OH:45].[CH:8](=[O:9])[c:10]1[cH:11][cH:12][cH:13][cH:14][cH:15]1.[Na+:29].[Na+:34].[OH:1][CH:2]1[CH2:3][NH:4][CH2:5][CH2:6][CH2:7]1>>[OH:1][CH:2]1[CH2:3][N:4]([CH2:8][c:10]2[cH:11][cH:12][cH:13][cH:14][cH:15]2)[CH2:5][CH2:6][CH2:7]1

Participants

8

Reactant 7

HCID 176Acetic AcidHCID 240BenzaldehydeHCID 769Bicarbonate IonHCID 923Sodium ion2×HCID 1140TolueneHCID 232933-HydroxypiperidineHCID 2724942Triacetoxyborohydride

Product 1

HCID 857731-Benzylpiperidin-3-ol

Sources & evidence

ORD record
ord-7fe8ab0bf48244b8b5e51a5ba5b8580a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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