Formic Acid → 1-[1-[3-[4-amino-3-chloro-5-(trifluoromethyl)phenyl]-2-[4-(2-oxo-4,5-dihydro-1H-1,3-benzodiazepin-3-yl)piperidine-1-carbonyl]oxypropanoyl]piperidin-4-yl]pyrrolidine-2-carboxylic acid
Reaction equation
[CH2:59]1[O:60][CH2:61][CH2:62][CH2:63]1.[CH:55]([OH:56])=[O:57].[Li+:2].[O:3]=[C:4]1[NH:5][c:6]2[c:7]([cH:51][cH:52][cH:53][cH:54]2)[CH2:8][CH2:9][N:10]1[CH:11]1[CH2:12][CH2:13][N:14]([C:17](=[O:18])[O:19][CH:20]([C:21](=[O:22])[N:23]2[CH2:24][CH2:25][CH:26]([N:29]3[CH:30]([C:34](=[O:35])[O:36][CH3:37])[CH2:31][CH2:32][CH2:33]3)[CH2:27][CH2:28]2)[CH2:38][c:39]2[cH:40][c:41]([Cl:50])[c:42]([NH2:49])[c:43]([C:45]([F:46])([F:47])[F:48])[cH:44]2)[CH2:15][CH2:16]1.[OH-:1].[OH2:58]>>[O:3]=[C:4]1[NH:5][c:6]2[c:7]([cH:51][cH:52][cH:53][cH:54]2)[CH2:8][CH2:9][N:10]1[CH:11]1[CH2:12][CH2:13][N:14]([C:17](=[O:18])[O:19][CH:20]([C:21](=[O:22])[N:23]2[CH2:24][CH2:25][CH:26]([N:29]3[CH:30]([C:34](=[O:35])[OH:36])[CH2:31][CH2:32][CH2:33]3)[CH2:27][CH2:28]2)[CH2:38][c:39]2[cH:40][c:41]([Cl:50])[c:42]([NH2:49])[c:43]([C:45]([F:46])([F:47])[F:48])[cH:44]2)[CH2:15][CH2:16]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-471b41584a7544bb90efd916d51478fb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…