p-Toluenesulfonic acid → HCID 19047547, compound

HRID 865965Notes

Reaction equation

HRID 865965 reaction equation
[O:1]1[CH:5]=[CH:4][C:3]([C:6]2(O)[C:14]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[CH2:8][CH2:7]2)=[CH:2]1.C1(C)C=CC(S(O)(=O)=O)=CC=1>C1(C)C=CC=CC=1>[O:1]1[CH:5]=[CH:4][C:3]([CH:6]2[C:14]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[CH:8]=[CH:7]2)=[CH:2]1

Participants

4

Reactant 2

HCID 6101p-Toluenesulfonic acidHCID 19047540HCID 19047540, compound

Product 1

HCID 19047547HCID 19047547, compoundYield 61.7%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

To a mixture of 5 g (0.024 mol) of 1-(3-furyl)-indan-1-ol in 500 ml of toluene was added 50 mg of p-toluenesulfonic acid and the mixture was placed on a Rotovap® and the solvent was distilled in vacuo (40 mm) until a residue was obtained. The residue was chromatographed (silica, 1:1 hexane/methylene chloride) to afford 2.7 g (61.3%) of 1-(3-furyl)-indene as a clear oil.

Workup

  1. distillationthe solvent was distilled in vacuo (40 mm) until a residue
  2. customwas obtained
  3. customThe residue was chromatographed (silica, 1:1 hexane/methylene chloride)

Sources & evidence

ORD record
ord-0625321083b64b389b215709cbf0fe34
Source dataset
uspto-grants-1996_10
Patent number
US05569655

Reaction notes

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