Methyl Isocyanate → HCID 54506864, compound

HRID 866644Notes

Reaction equation

HRID 866644 reaction equation
[N:1](=[C:3]1[C:8]([CH3:10])([CH3:9])[O:7][CH2:6][CH2:5][O:4]1)[OH:2].[CH3:11][N:12]=[C:13]=[O:14]>C(N(CC)CC)C>[CH3:9][C:8]1([CH3:10])[O:7][CH2:6][CH2:5][O:4][C:3]1=[N:1][O:2][C:13](=[O:14])[NH:12][CH3:11]

Participants

4

Reactant 2

HCID 12228Methyl IsocyanateHCID 73676197HCID 73676197, compound

Product 1

HCID 54506864HCID 54506864, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineCatalyst

Procedure

To a solution of 16.8 g of crude 2-oximino-3,3-dimethyl-1,4-dioxane and 2 drops of triethylamine was added 17 ml of methyl isocyanate. The reaction mixture was left at ambient temperature for 16 hours. The reaction mixture was concentrated and filtered to yield 4.0 g of 3,3-dimethyl-2-[O-(methylcarbamoyl)oximino]-1,4-dioxane, m.p. 144°-146° C. (m/e 202).

Workup

  1. concentrationThe reaction mixture was concentrated
  2. filtrationfiltered

Sources & evidence

ORD record
ord-9b39d16da37440e19570d9e598e1c75b
Source dataset
uspto-grants-1978_07
Patent number
US04100295

Reaction notes

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