Thionyl Chloride → HCID 22750308, compound

HRID 866987Notes

Reaction equation

HRID 866987 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[NH:7][S:8]([C:11]1[CH:16]=[CH:15][C:14]([C:17]2[NH:18][C:19](=[O:26])[C:20](=[CH:24][CH:25]=2)[C:21](O)=O)=[CH:13][CH:12]=1)(=[O:10])=[O:9].S(Cl)([Cl:29])=O.NS(C1C=CC(C2NC(=O)C(=CC=2)C[Cl:46])=CC=1)(=O)=O>CN(C)C=O>[ClH:29].[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[NH:7][S:8]([C:11]1[CH:16]=[CH:15][C:14]([C:17]2[NH:18][C:19](=[O:26])[C:20](=[CH:24][CH:25]=2)[CH2:21][Cl:46])=[CH:13][CH:12]=1)(=[O:10])=[O:9]

Participants

5

Reactant 3

HCID 24386Thionyl ChlorideHCID 22750325HCID 22750325, compoundHCID 22750339HCID 22750339, compound

Product 1

HCID 22750308HCID 22750308, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

From 7.0 g. of 6-[4-(2-pyridylaminosulfonyl)phenyl]-1,2-dihydro-2-oxonicotinic acid in 200 ml. of thionyl chloride, and 1.5 ml. of dimethylformamide, following the procedure of (c) above, there is obtained 6-[4-(2-pyridylaminosulfonyl)phenyl]-1,2-dihydro-2-oxonicotinyl chloride hydrochloride.

Sources & evidence

ORD record
ord-3794cb1fd18d4136aabc704ef68abf69
Source dataset
uspto-grants-1978_07
Patent number
US04101661

Reaction notes

Loading…