Acetic Acid → 2',4'-Dihydroxyacetophenone

HRID 868005Notes

Reaction equation

HRID 868005 reaction equation
[C:1]1([CH:8]=[CH:7][CH:6]=[C:4]([OH:5])[CH:3]=1)[OH:2].Br.[C:10](O)(=[O:12])[CH3:11]>>[OH:2][C:1]1[CH:8]=[CH:7][C:6]([C:10](=[O:12])[CH3:11])=[C:4]([OH:5])[CH:3]=1

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 260Hydrogen BromideHCID 5054Resorcinol

Product 1

HCID 69902',4'-Dihydroxyacetophenone

Procedure

A process of claim 1, wherein 1,3-dihydroxy-4-acetylbenzene is prepared by combining resorcinol with acetic acid and hydrobromic acid at a temperature between about the boiling point of the reaction mixture to about 75° C. for between about one hour to about five days.

Workup

  1. customto about 75° C.
  2. customfor between about one hour to about five days

Sources & evidence

ORD record
ord-ecc64d54c44c4120bc2d761562ba3a87
Source dataset
uspto-grants-1988_10
Patent number
US04777298

Reaction notes

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