Hydrochloric Acid → HCID 70388211, compound

HRID 868023Notes

Reaction equation

HRID 868023 reaction equation
[NH:1]1[CH:5]=[CH:4][N:3]=[C:2]1[CH2:6][CH:7]1[CH2:16][CH2:15][C:14]2[CH:13]=[C:12]([C:17]([O:19][CH2:20][CH3:21])=[O:18])[CH:11]=[CH:10][C:9]=2[CH2:8]1.[ClH:22]>C(O)C>[ClH:22].[NH:1]1[CH:5]=[CH:4][N:3]=[C:2]1[CH2:6][CH:7]1[CH2:16][CH2:15][C:14]2[CH:13]=[C:12]([C:17]([O:19][CH2:20][CH3:21])=[O:18])[CH:11]=[CH:10][C:9]=2[CH2:8]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 70388212HCID 70388212, compound

Product 1

HCID 70388211HCID 70388211, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

1.3 g of ethyl 6-(1-imidazolylmethyl)-5,6,7,8-tetrahydro-2-naphthalenecarboxylate was mixed with 15 ml of a 5% solution of hydrogen chloride in ethanol, and the mixture was concentrated to dryness in vacuo. The residue was recrystallized from a mixture of isopropanol and diethyl ether to give 1.2 g of ethyl 6-(1-imidazolylmethyl)-5,6,7,8-tetrahydro-2-naphthalenecarboxylate hydrochloride as colorless crystals with m.p. 180°-182° C.

Workup

  1. concentrationthe mixture was concentrated to dryness in vacuo
  2. customThe residue was recrystallized from a mixture of isopropanol and diethyl ether

Sources & evidence

ORD record
ord-e272452a1e5e47e085cca21bc1ad8c04
Source dataset
uspto-grants-1988_10
Patent number
US04777257

Reaction notes

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