Benzaldehyde → HCID 21287654, compound

HRID 868685Notes

Reaction equation

HRID 868685 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[NH:8]/[C:9](/[CH3:15])=[CH:10]\[C:11]([O:13][CH3:14])=[O:12].[CH:16](=O)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>C1C=CC=CC=1>[CH3:15][C:9]1[N:8]([C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[CH3:1])[C:9]([CH3:15])=[C:10]([C:11]([O:13][CH3:14])=[O:12])[CH:16]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[C:10]=1[C:11]([O:13][CH3:14])=[O:12]

Participants

4

Reactant 2

HCID 240BenzaldehydeHCID 67938254HCID 67938254, compound

Product 1

HCID 21287654HCID 21287654, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

A solution of 4.1 grams (20 millimoles) of methyl 3-(2-methylphenyl)aminocrotonate in 5 milliliters of dry benzene is added to the titanamine complex followed by 1.1 grams (10 millimoles) of benzaldehyde and the mixture stirred at ambient temperature for several hours to obtain the desired dimethyl 2,6-dimethyl-4-phenyl-1-(2-methylphenyl)-1,4-dihydropyridine-3,5-dicarboxylate which may be recovered in a manner similar to that previously described.

Sources & evidence

ORD record
ord-1859e008b4b74498bc5f38b89dcabfd6
Source dataset
uspto-grants-1988_10
Patent number
US04780538

Reaction notes

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