反应详情

温度

130 °C

1H-Imidazole-2(3H)-thione (241 mg, 0.92 mmol) and 2-chloroquinoxaline (166 mg, 1.01 mmol) were combined in anhydrous THF (10 mL) in a microwave vial. To the suspension was added Hunig's base (320 μL, 1.84 mmol). The resulting clear yellow solution was heated in the microwave (130° C., 30 min), then concentrated and purified by column chromatography. 2-(4-Phenyl-1H-imidazol-2-ylthio)quinoxaline was obtained as a yellowish oil. LC-MS m/z 305 (M+H+).

1. concentrationconcentrated
2. custompurified by column chromatography