Acetone → 3-fluoro-4-(2-(4-methylpyridin-2-ylamino)thiazol-5-ylthio)-N-(3-oxo-2,2-diphenylpropyl)picolinamide
Reaction equation
[C:44](=[O:45])([OH:46])[O-:47].[CH2:54]1[O:55][CH2:56][CH2:57][CH2:58]1.[CH3:49][C:50](=[O:51])[CH3:52].[ClH:59].[Na+:48].[O:1]1[CH:2]([C:6]([CH2:7][NH:8][C:9]([c:10]2[c:11]([F:30])[c:12]([S:16][c:17]3[cH:18][n:19][c:20]([NH:22][c:23]4[n:24][cH:25][cH:26][c:27]([CH3:29])[cH:28]4)[s:21]3)[cH:13][cH:14][n:15]2)=[O:31])([c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[c:38]2[cH:39][cH:40][cH:41][cH:42][cH:43]2)[O:5][CH2:4][CH2:3]1.[OH2:53]>>[O:1]=[CH:2][C:6]([CH2:7][NH:8][C:9]([c:10]1[c:11]([F:30])[c:12]([S:16][c:17]2[cH:18][n:19][c:20]([NH:22][c:23]3[n:24][cH:25][cH:26][c:27]([CH3:29])[cH:28]3)[s:21]2)[cH:13][cH:14][n:15]1)=[O:31])([c:32]1[cH:33][cH:34][cH:35][cH:36][cH:37]1)[c:38]1[cH:39][cH:40][cH:41][cH:42][cH:43]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-d215923785574bebb86f0426aa60f59b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…