Trifluoroacetic acid → 5-(4,5-dihydrothiazol-5-yl)-3-(1-methylpiperidin-4-yl)-1H-indole
Reaction equation
[CH2:22]([SiH:23]([CH2:24][CH3:25])[CH2:26][CH3:27])[CH3:28].[OH:29][C:30]([C:31]([F:32])([F:33])[F:34])=[O:35].[S:1]1[CH:2]=[N:3][CH2:4][CH:5]1[c:6]1[cH:7][c:8]2[c:9]([C:15]3=[CH:20][CH2:19][N:18]([CH3:21])[CH2:17][CH2:16]3)[cH:10][nH:11][c:12]2[cH:13][cH:14]1>>[S:1]1[CH:2]=[N:3][CH2:4][CH:5]1[c:6]1[cH:7][c:8]2[c:9]([CH:15]3[CH2:16][CH2:17][N:18]([CH3:21])[CH2:19][CH2:20]3)[cH:10][nH:11][c:12]2[cH:13][cH:14]1Participants
4
Sources & evidence
- ORD record
- ord-82ec06c1e739450c9680c08a78fec40f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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