Fluorene → HCID 22568535, compound

HRID 871194Notes

Reaction equation

HRID 871194 reaction equation
[CH:1]1[C:13]2[CH2:12][C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[CH:4]=[CH:3][CH:2]=1.[Li]CCCC.Br[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37]>C1CCCCC1>[CH2:37]([CH:12]1[C:11]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[C:5]2[C:13]1=[CH:1][CH:2]=[CH:3][CH:4]=2)[CH2:36][CH2:35][CH2:34][CH2:33][CH2:32][CH2:31][CH2:30][CH2:29][CH2:28][CH2:27][CH2:26][CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH3:20]

Participants

5

Reactant 3

HCID 6853FluoreneHCID 82181-BromooctadecaneHCID 178418339Butyllithium

Product 1

HCID 22568535HCID 22568535, compoundYield 88%

Reagents, catalysts & solvents 1

HCID 8078CyclohexaneSolvent

Procedure

Fluorene (7.0 g, 42.1 mmol), n-BuLi (17.35 ml, 43.4 mmol, 2.5 M in hexane), RX=1-bromooctadecane (14.53 g, 43.6 mmol). Following the usual workup 44 was isolated as a white solid (15.5 g, 88%), Rf 0.73 (cyclohexane).

Sources & evidence

ORD record
ord-5b047e7a2f364f53b7e94fa5b78fa29e
Source dataset
uspto-grants-2015_03
Patent number
US08969624B2

Reaction notes

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