Ammonium → N-(4-propoxyphenylmethyl)-4-[(4-trifluoromethoxyphenyl)(4-chlorophenyl)hydroxymethyl]piperidine
Reaction equation
[Br-:31].[CH2:1]([CH2:2][CH3:3])[O:4][c:5]1[cH:6][cH:7][c:8]([CH2:11][N:12]2[CH2:13][CH2:14][CH:15]([C:18](=[O:19])[c:20]3[cH:21][cH:22][c:23]([O:26][C:27]([F:28])([F:29])[F:30])[cH:24][cH:25]3)[CH2:16][CH2:17]2)[cH:9][cH:10]1.[Cl-:40].[Cl:32][c:33]1[cH:34][cH:35][c:36]([Mg+:39])[cH:37][cH:38]1.[NH4+:41].[O:42]1[CH2:43][CH2:44][CH2:45][CH2:46]1>>[CH2:1]([CH2:2][CH3:3])[O:4][c:5]1[cH:6][cH:7][c:8]([CH2:11][N:12]2[CH2:13][CH2:14][CH:15]([C:18]([OH:19])([c:20]3[cH:21][cH:22][c:23]([O:26][C:27]([F:28])([F:29])[F:30])[cH:24][cH:25]3)[c:36]3[cH:35][cH:34][c:33]([Cl:32])[cH:38][cH:37]3)[CH2:16][CH2:17]2)[cH:9][cH:10]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-18799d7446dc4796b031cd525ce384c0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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