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HRID879235

反应详情

EQUATION

反应方程式

HRID 879235 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)C(F)(F)F
HCID6422

未命名化合物

结构：CC[C@H](C)[C@@H]([C@@H](CC(=O)OC(C)(C)C)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C(=O)OCC1c2ccccc2-c2ccccc21)C(C)C
HCID71294595

未命名化合物

2 次

PRODUCTS

生成物

1
结构：CC[C@H](C)[C@@H]([C@@H](CC(=O)O)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C(=O)OCC1c2ccccc2-c2ccccc21)C(C)C
HCID60042710

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

650 mg (0.94 mmol) N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-valyl-N-[(3R,4S,5S)-1-tert.-butoxy-3-methoxy-5-methyl-1-oxoheptane-4-yl]-N-methyl-L-valinamide (intermediate 3) were absorbed by 5 ml dichlormethane, 5 ml trifluoroacetic acid were added and then stirred overnight at RT. Then, the mixture was evaporated in vacuum and the remaining residue was purified using HPLC. 430 mg (72% o. th.) of the title compound were obtained as a colorless foam.

WORKUP

后处理

  1. additionwere added
  2. customThen, the mixture was evaporated in vacuum
  3. customthe remaining residue was purified