Acetate → Tert-butyl 5-cyclopropyl-4-[3-[(2-methylpropan-2-yl)oxycarbonylamino]piperidin-1-yl]-3-(pyridine-3-carbonylamino)pyrrolo[2,3-b]pyridine-1-carboxylate
Reaction equation
[Br:1][c:2]1[c:3]([N:27]2[CH2:28][CH:29]([NH:33][C:34](=[O:35])[O:36][C:37]([CH3:38])([CH3:39])[CH3:40])[CH2:30][CH2:31][CH2:32]2)[c:4]2[c:5]([n:6][cH:7]1)[n:8]([C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[cH:9][c:10]2[NH:11][C:12]([c:13]1[cH:14][n:15][cH:16][cH:17][cH:18]1)=[O:19].[CH:41]1([B:44]([OH:45])[OH:46])[CH2:42][CH2:43]1.[CH:55]1([P:56]([CH:57]2[CH2:58][CH2:59][CH2:60][CH2:61][CH2:62]2)[CH:63]2[CH2:64][CH2:65][CH2:66][CH2:67][CH2:68]2)[CH2:69][CH2:70][CH2:71][CH2:72][CH2:73]1.[K+:52].[K+:53].[K+:54].[O-:83][C:84]([CH3:85])=[O:86].[O-:87][C:88]([CH3:89])=[O:90].[OH2:74].[P:47]([O-:48])([O-:49])([O-:50])=[O:51].[Pd+2:82].[c:75]1([CH3:76])[cH:77][cH:78][cH:79][cH:80][cH:81]1>>[c:2]1([CH:41]2[CH2:42][CH2:43]2)[c:3]([N:27]2[CH2:28][CH:29]([NH:33][C:34](=[O:35])[O:36][C:37]([CH3:38])([CH3:39])[CH3:40])[CH2:30][CH2:31][CH2:32]2)[c:4]2[c:5]([n:6][cH:7]1)[n:8]([C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[cH:9][c:10]2[NH:11][C:12]([c:13]1[cH:14][n:15][cH:16][cH:17][cH:18]1)=[O:19]Participants
10
Reactant 9
Product 1
Sources & evidence
- ORD record
- ord-0e10c9836a31459f989c17ad8a85ab22
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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