Triethylamine → (4-Bromo-2-phenylethynyl-thiazol-5-yl)-piperidin-1-yl-methanone

HRID 88073Notes

Reaction equation

HRID 88073 reaction equation
[Br:1][c:2]1[s:3][c:4]([C:8](=[O:9])[N:10]2[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]2)[c:5]([Br:7])[n:6]1.[CH3:24][CH2:25][N:26]([CH2:27][CH3:28])[CH2:29][CH3:30].[Cu:31][I:32].[c:16]1([C:22]#[CH:23])[cH:17][cH:18][cH:19][cH:20][cH:21]1>>[c:2]1([C:23]#[C:22][c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[s:3][c:4]([C:8](=[O:9])[N:10]2[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]2)[c:5]([Br:7])[n:6]1

Participants

5

Reactant 4

HCID 8471TriethylamineHCID 10821PhenylacetyleneHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 58227559Methanone, (2,4-dibromo-5-thiazolyl)-1-piperidinyl-

Product 1

HCID 58227508(4-Bromo-2-phenylethynyl-thiazol-5-yl)-piperidin-1-yl-methanone

Sources & evidence

ORD record
ord-947e67cf91b34964a320e5397c1cacd6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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