反应详情

The product from Example 44A (995 mg, 3.77 mmol) was reacted with 4-chloro-3-nitro-phenol (650 mg, 3.77 mmol) in 15 mL of DMF with K2CO3 (10.4 g, 3.77 mmol) at 80° C. for 3 h. Cooled to room temperature and diluted with water. Extracted with CH2Cl2, washed four times with water. Dried over Na2SO4, filtered and concentrated under vacuum giving the title compound (1.24 g, 92%).

1. extractionExtracted with CH2Cl2
2. washwashed four times with water
3. dry with materialDried over Na2SO4
4. filtrationfiltered
5. concentrationconcentrated under vacuum