Chloroform → HCID 131729879, compound
Reaction equation
[CH3:1][C@H:2]([OH:6])[C:3]([OH:5])=[O:4].[CH3:7][N:8]([CH3:11])[CH:9]=[O:10].[CH:12]([Cl:15])([Cl:14])[Cl:13]>[Au]>[CH3:1][C@H:2]([OH:6])[C:3]([OH:5])=[O:4].[CH:12]([Cl:15])([Cl:14])[Cl:13].[CH3:7][N:8]([CH3:11])[CH:9]=[O:10]Participants
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
A membrane was prepared as follows: a 1 wt % PLLA/chloroform/N,N-dimethyl formamide (DMF) solution was prepared by slowly dissolving PLLA pellets (inherent viscosity of 7.0 dl/g, PURAC, Netherlands) into a chloroform solvent at room temperature with stirring. After PLLA was completely dissolved, 10 wt % DMF was added. The solution was then loaded into the 20 ml syringe fitted with a needle, and delivered to an electrode. The solution was pumped and controlled by a syringe pump at a flow rate of 0.3 ml/min. A 10 kV positive high voltage was applied on the electrode. The distance from the tip of the electrode to the grounded collecting plate was 15 cm. A tiny electrospinning jet was formed and stabilized in 30 seconds under these conditions. The collecting plate was movable and controlled by a stepper motor. The collecting plate was continually moved at a rate of 1 mm/sec until a membrane having a relatively uniform thickness of about 100 microns was obtained. Electrospun membranes were sputtered with gold, and their morphology was observed under a scanning electron microscopy (SEM).
Workup
- customA membrane was prepared
- customfitted with a needle
- customcontrolled by a syringe
- customThe distance from the tip of the electrode to the grounded collecting plate
- customA tiny electrospinning jet was formed
- customwas obtained
Sources & evidence
- ORD record
- ord-c24bea4a992047fdbebb4a863f925d8b
- Source dataset
- uspto-grants-2012_08
- Patent number
- US08242073B2
Reaction notes
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