Toluene → Ethyl 2,2-difluoro-3-(4-methoxyphenyl)propanoate
Reaction equation
[CH2:19]([SnH:20]([CH2:21][CH2:22][CH2:23][CH3:24])[CH2:25][CH2:26][CH2:27][CH3:28])[CH2:29][CH2:30][CH3:31].[CH3:44][c:45]1[cH:46][cH:47][cH:48][cH:49][cH:50]1.[F:1][C:2]([C:3](=[O:4])[O:5][CH2:6][CH3:7])([CH:8]([c:9]1[cH:10][cH:11][c:12]([O:15][CH3:16])[cH:13][cH:14]1)[I:17])[F:18].[N:32]([C:33]([CH3:34])([CH3:35])[C:36]#[N:37])=[N:38][C:39]([CH3:40])([CH3:41])[C:42]#[N:43]>>[F:1][C:2]([C:3](=[O:4])[O:5][CH2:6][CH3:7])([CH2:8][c:9]1[cH:10][cH:11][c:12]([O:15][CH3:16])[cH:13][cH:14]1)[F:18]Participants
5
Sources & evidence
- ORD record
- ord-349a8eb054254b1aa9f27cac008bb019
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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