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HRID885292

反应详情

EQUATION

反应方程式

HRID 885292 的结构方程式

REACTANTS

反应物

2
结构：[Li+].[OH-]
HCID3939

Lithium hydroxide anhydrous

HLiO

结构：CCOC(=O)Cc1cc(Oc2ccc(Br)cc2CN2C(=O)O[C@H](c3ccccc3)[C@@H]2C)ccc1Cl
HCID58237555

未命名化合物

PRODUCTS

生成物

1
结构：C[C@H]1[C@@H](c2ccccc2)OC(=O)N1Cc1cc(Br)ccc1Oc1ccc(Cl)c(CC(=O)O)c1
HCID44188253

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1COCCO1
溶剂HCID31275

1,4-Dioxane

C4H8O2

PROCEDURE

实验过程

Hydrolysis of {5-[4-bromo-2-((4S,5R)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-ylmethyl)-phenoxy]-2-chloro-phenyl}-acetic acid ethyl ester (0.32 mmol) in 1,4-dioxane with aqueous lithium hydroxide, followed by purification by preparative HPLC, gave the desired product.

WORKUP

后处理

  1. customfollowed by purification by preparative HPLC