Dimethylformamide → 2-Aza-bicyclo[2.2.1]heptane-2,3-dicarboxylic acid 3-(2-{9-[2-(1-tert-butoxycarbonyl-pyrrolidine-2-carbonyloxy)-acetyl]-5,7-dihydro-dibenzo[c,e]oxepin-3-yl}-2-oxo-ethyl) ester 2-tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]2[CH2:10][CH2:11][CH:12]([CH:13]1[C:14](=[O:15])[OH:16])[CH2:17]2.[C:25]([CH3:26])([CH3:27])([CH3:28])[O:29][C:30](=[O:31])[N:32]1[CH:33]([C:37](=[O:38])[O:39][CH2:40][C:41](=[O:42])[c:43]2[cH:44][cH:45][c:46]3[c:47]([cH:61]2)[CH2:48][O:49][CH2:50][c:51]2[c:52]-3[cH:53][cH:54][c:55]([C:57]([CH2:58][Br:59])=[O:60])[cH:56]2)[CH2:34][CH2:35][CH2:36]1.[CH3:18][CH2:19][N:20]([CH2:21][CH3:22])[CH2:23][CH3:24].[CH3:62][C:63]#[N:64].[O:65]=[CH:66][N:67]([CH3:68])[CH3:69]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]2[CH2:10][CH2:11][CH:12]([CH:13]1[C:14](=[O:15])[O:16][CH2:58][C:57]([c:55]1[cH:54][cH:53][c:52]3[c:51]([cH:56]1)[CH2:50][O:49][CH2:48][c:47]1[c:46]-3[cH:45][cH:44][c:43]([C:41]([CH2:40][O:39][C:37]([CH:33]3[N:32]([C:30]([O:29][C:25]([CH3:26])([CH3:27])[CH3:28])=[O:31])[CH2:36][CH2:35][CH2:34]3)=[O:38])=[O:42])[cH:61]1)=[O:60])[CH2:17]2Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-bbabe8ff8a7d44bdbf50f1b7f7acfde2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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