Acetic Acid → HCID 75985013, compound

HRID 885781Notes

Reaction equation

HRID 885781 reaction equation
Br[CH2:2][C:3]([O:11][CH3:12])=[CH:4][C:5](=[O:10])[C:6]([Cl:9])([Cl:8])[Cl:7].[C:13]([O-:16])(=[O:15])[CH3:14].[Cs+].C(O)(=O)C>[Br-].C([N+](CCCC)(CCCC)CCCC)CCC.C(#N)C>[C:13]([O:16][CH2:2][C:3]([O:11][CH3:12])=[CH:4][C:5](=[O:10])[C:6]([Cl:9])([Cl:8])[Cl:7])(=[O:15])[CH3:14]

Participants

6

Reactant 3

HCID 176Acetic AcidHCID 5152919Cesium acetateHCID 72820289HCID 72820289, compound

Product 1

HCID 75985013HCID 75985013, compound

Reagents, catalysts & solvents 2

HCID 74236Tetrabutylammonium BromideCatalystHCID 6342AcetonitrileSolvent

Procedure

29.6 g (0.1 mol) of 5-bromo-1,1,1-trichloro-4-methoxypent-3-en-2-one, 19.1 g of cesium acetate, 5 g of tetrabutylammonium bromide and 8 g of acetic acid were stirred in 300 ml of acetonitrile at 25° C. for 8 h. The precipitate was filtered off and the organic phase was concentrated under reduced pressure.

Workup

  1. filtrationThe precipitate was filtered off
  2. concentrationthe organic phase was concentrated under reduced pressure

Sources & evidence

ORD record
ord-5ffabc4cae3249539d639ab5c2871d7e
Source dataset
uspto-grants-2012_08
Patent number
US08242313B2

Reaction notes

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