反应详情

A mixture of tert-butyl 9-(2-methyl-3-furyl)-2,3-dihydro-1,4-benzoxazepine-4(5H)-carboxylate (300 mg, 0.911 mmol), ethyl acetate (1 ml) and 4N hydrogen chloride-ethyl acetate solution (3 ml) was stirred at room temperature for 0.5 hr, and the solvent was evaporated under reduced pressure. The residue was recrystallized from a mixed solvent of methanol and ether to give the desired product (230 mg, 95.0%) as a solid.

1. customthe solvent was evaporated under reduced pressure
2. customThe residue was recrystallized from a mixed solvent of methanol and ether