Dibromomethane → HCID 178426248, compound

HRID 888270Notes

Reaction equation

HRID 888270 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH:12]=[CH:11][N:10]=[CH:9]2)=[CH:4][CH:3]=1.[Br:13]CBr.[CH2:16]1[CH2:20]O[CH2:18][CH2:17]1>>[Br-:13].[Br-:13].[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([N+:8]2[CH:12]=[CH:11][N:10]([CH2:5][N:8]3[CH:12]=[CH:11][N+:10]([C:16]4[CH:20]=[CH:1][C:2]([CH3:3])=[CH:18][CH:17]=4)=[CH:9]3)[CH:9]=2)=[CH:6][CH:7]=1

Participants

4

Reactant 3

HCID 3024DibromomethaneHCID 8028TetrahydrofuranHCID 53029351-(4-methylphenyl)imidazole

Product 1

HCID 178426248HCID 178426248, compound

Procedure

0.013 mol of 1-(4-methylphenyl)imidazole (2.000 g), 0.0063 mol of dibromomethane (1.099 g; 0.45 ml) and 5 ml of THF are stirred in a pressure tube at room temperature overnight and then at 120° C. for 9 hours. The precipitated solid is filtered off and washed repeatedly with a little tetrahydrofuran.

Workup

  1. filtrationThe precipitated solid is filtered off
  2. washwashed repeatedly with a little tetrahydrofuran

Sources & evidence

ORD record
ord-b5b18caf86114c2aa35dac328053544f
Source dataset
uspto-grants-2012_08
Patent number
US08247574B2

Reaction notes

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