Hydrazine hydrate (1:1) → N-(3-Methyl-isoxazol-5-yl)-hydrazinecarboxamide

HRID 889152Notes

Reaction equation

HRID 889152 reaction equation
O.[NH2:2][NH2:3].C1([O:10][C:11](=O)[NH:12][C:13]2[O:17][N:16]=[C:15]([CH3:18])[CH:14]=2)C=CC=CC=1>C(O)C>[CH3:18][C:15]1[CH:14]=[C:13]([NH:12][C:11]([NH:2][NH2:3])=[O:10])[O:17][N:16]=1

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 22936635Phenyl (3-methylisoxazol-5-yl)carbamate

Product 1

HCID 57927573N-(3-Methyl-isoxazol-5-yl)-hydrazinecarboxamide

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Hydrazine hydrate (95 μl) was added to a mixture of (3-methyl-isoxazol-5-yl)-carbamic acid phenyl ester (CA 81479-55-2) (417 mg) and ethanol (5 ml), and the resulting mixture was stirred overnight at room temperature. The precipitate was collected by filtration to obtain the title compound (100 mg).

Workup

  1. filtrationThe precipitate was collected by filtration

Sources & evidence

ORD record
ord-b9750ba282474cbc9934fa597714b169
Source dataset
uspto-grants-2012_08
Patent number
US08252810B2

Reaction notes

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