9-Borabicyclo(3.3.1)nonane → HCID 178419117, compound

HRID 889265Notes

Reaction equation

HRID 889265 reaction equation
[CH3:1][C:2]([CH3:9])([CH2:6][CH:7]=[CH2:8])[C:3]([OH:5])=[O:4].[BH:10]1[CH:15]2[CH2:16][CH2:17][CH2:18][CH:11]1[CH2:12][CH2:13][CH2:14]2>C1COCC1>[CH3:1][C:2]([CH3:9])([CH2:6][CH:7]=[CH2:8])[C:3]([OH:5])=[O:4].[BH:10]1[CH:15]2[CH2:16][CH2:17][CH2:18][CH:11]1[CH2:12][CH2:13][CH2:14]2

Participants

4

Reactant 2

HCID 789669-Borabicyclo(3.3.1)nonaneHCID 1400652,2-Dimethyl-4-pentenoic acid

Product 1

HCID 178419117HCID 178419117, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Conditions

Temperature
0 °C

Procedure

To a solution of 2,2-dimethyl-pent-4-enoic acid (500 mg, 3.0 mmol) in THF (4 mL) is added 9-BBN (0.5M, 17 mL, 3.0 mmol) at 0° C. and it is stirred at 0° C. for 2 h. The solvent is removed via vacuum to give the title compound and it is used directly in the next step.

Workup

  1. customThe solvent is removed via vacuum

Sources & evidence

ORD record
ord-6fa0797e48174ab7a51b35b93334b9b5
Source dataset
uspto-grants-2012_08
Patent number
US08252820B2

Reaction notes

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