Tert-Butylamine → N-(1,1-Dimethylethyl)benzenesulfonamide

HRID 891968Notes

Reaction equation

HRID 891968 reaction equation
[C:1]1([S:7](Cl)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:11]([NH2:15])([CH3:14])([CH3:13])[CH3:12]>N1C=CC=CC=1>[C:11]([NH:15][S:7]([C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)(=[O:9])=[O:8])([CH3:14])([CH3:13])[CH3:12]

Participants

4

Reactant 2

HCID 6385Tert-ButylamineHCID 7369Benzenesulfonyl chloride

Product 1

HCID 314059N-(1,1-Dimethylethyl)benzenesulfonamide

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Conditions

Temperature
35 °C

Procedure

9.6 ml (75 mmol) of benzenesulphonic acid chloride are placed in 100 ml pyridine and 7.9 ml (75 mmol) of tert.butylamine are added dropwise at 5° C., whereupon the temperature increases to 35° C. After the addition has ended the mixture is stirred for another hour at 35° C. Then it is poured onto ice water and the crystalline precipitate is suction filtered.

Workup

  1. additionAfter the addition
  2. additionThen it is poured onto ice water
  3. filtrationfiltered

Sources & evidence

ORD record
ord-2d8ab41b387443d888bab91f0f29e3ad
Source dataset
uspto-grants-2006_02
Patent number
US07005437B2

Reaction notes

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