反应详情

35 mg (0.15 mmol) 75% 3-chloroperoxybenzoic acid dissolved in 5 ml ethyl acetate were given at −30° C. to solution of 52 mg (0.10 mmol) 1-[2-(2-methyl-4-{2-[2-(E)-(4-trifluoromethoxy-phenyl)-vinyl]-oxazol-4-ylmethoxy}-phenyl-methanesulfinyl)-ethyl]-1H[1,2,3]triazole in 25 ml dichloromethane. The mixture was stirred for 48 h and slowly allowed to reach room temperature. Additional 20 ml dichloromethane were added, washed with conc. sodium carbonate solution, water, dried and evaporated to give 29 mg (53%) of the title compound.

1. customto reach room temperature
2. washwashed with conc. sodium carbonate solution, water
3. customdried
4. customevaporated