2,6-Diisopropylphenyl isocyanate → HCID 57081079, compound

HRID 892477Notes

Reaction equation

[C:1]12[CH2:15][CH2:14][C:13](=[O:16])[C:12]=1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]2.[CH:17]([C:20]1[CH:25]=[CH:24][CH:23]=[C:22]([CH:26]([CH3:28])[CH3:27])[C:21]=1[N:29]=[C:30]=[O:31])([CH3:19])[CH3:18].C([N-]C(C)C)(C)C.[Li+]>>[CH3:19][CH:17]([C:20]1[CH:25]=[CH:24][CH:23]=[C:22]([CH:26]([CH3:27])[CH3:28])[C:21]=1[NH:29][C:30]([CH:14]1[C:13](=[O:16])[C:12]2[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2][C:1]=2[CH2:15]1)=[O:31])[CH3:18]

Participants

Reactant 3

HCID 922592,6-Diisopropylphenyl isocyanate

HCID 2724682Lithium diisopropylamide

HCID 110313982,3,4,5,6,7,8,9,10,11,12,13-Dodecahydro-1H-cyclopentacyclododecen-1-one

Product 1

HCID 57081079HCID 57081079, compound

Procedure

The title compound, mp 225°-229° C., was prepared from bicyclo[10.3.0]pentadec-12(1)-en-13 one (5.0 g, 0.022 mol), 2,6-diisopropylphenyl isocyanate (4.60 g, 0.022 mol), and lithium diisopropylamide (0.022 mol) using the procedure described in Example 1. ##STR12##

Sources & evidence

ORD record: ord-ed50f3aa22844c6dab184f09ca5a34a5
Source dataset: uspto-grants-1992_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05118697

Reaction notes

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