Ethyl Acetate → 2-(6-bromo-2,2-dimethyl-2H-1-benzopyran-4-yl)pyridine N-oxide

HRID 892568Notes

Reaction equation

[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[O:10][C:9]([CH3:12])([CH3:11])[CH:8]=[C:7]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=3)[C:6]=2[CH:19]=1.C(OCC)(=[O:22])C>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[O:10][C:9]([CH3:12])([CH3:11])[CH:8]=[C:7]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][N+:14]=3[O-:22])[C:6]=2[CH:19]=1

Participants

Reactant 2

HCID 8857Ethyl Acetate

HCID 198955876-bromo-2,2-dimethyl-4-(2-pyridyl)-2H-1-benzopyran

Product 1

HCID 536691392-(6-bromo-2,2-dimethyl-2H-1-benzopyran-4-yl)pyridine N-oxide

Procedure

In an analogous manner to that described in the first paragraph of Example 6, from 6-bromo-2,2-dimethyl-4-(2-pyridyl)-2H-1-benzopyran there was obtained 2-(6-bromo-2,2-dimethyl-2H-1-benzopyran-4-yl)pyridine N-oxide of melting point 146°-148° C. (from ethyl acetate).

Sources & evidence

ORD record: ord-e3a0fd2f092140009a9b8c0b747ecb34
Source dataset: uspto-grants-1992_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05118694

Reaction notes

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