反应详情

A mixture of 296 grams (g) (2.37 mol) of t-butyl hydrazine hydrochloride, 20 milliliters (mL) of concentrated hydrochloric acid (HCl) and 2 liters (L) of water was stirred at room temperature to give a clear solution. Benzoylformic acid (400 g, 2.61 mol) was added in four equal portions at 3 minute intervals. The mixture was stirred overnight at room temperature and filtered. The solid collected was washed with water and dried in vacuo to furnish 520 g (99%) of the compound, mp 138°-139° C.

1. customto give a clear solution
2. stirringThe mixture was stirred overnight at room temperature
3. filtrationfiltered
4. customThe solid collected
5. washwas washed with water
6. customdried in vacuo